Title |
Gram Negative Bacteria Are Associated with the Early Stages of Necrotizing Enterocolitis
|
---|---|
Published in |
PLOS ONE, March 2011
|
DOI | 10.1371/journal.pone.0018084 |
Pubmed ID | |
Authors |
Erica M. Carlisle, Valeriy Poroyko, Michael S. Caplan, John A. Alverdy, Donald Liu |
Abstract |
Necrotizing enterocolitis (NEC) affects 5-10% of infants born weighing less than 1500 g. Most models of NEC recapitulate late-stage disease with gut necrosis and elevated inflammatory mediators. Evaluation of NEC at earlier, less lethal stages of disease will allow investigation of initial disease triggers and may advance our understanding of temporal relationships between factors implicated in NEC pathogenesis. In this manuscript, we describe our investigation of early NEC and test the hypothesis that bacteria and inflammatory mediators differ between animals with early NEC and disease free animals. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Cameroon | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 3% |
Italy | 2 | 3% |
France | 1 | 1% |
Unknown | 72 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 19% |
Researcher | 15 | 19% |
Student > Master | 12 | 16% |
Student > Bachelor | 6 | 8% |
Student > Doctoral Student | 6 | 8% |
Other | 10 | 13% |
Unknown | 13 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 27% |
Medicine and Dentistry | 20 | 26% |
Immunology and Microbiology | 6 | 8% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 7 | 9% |
Unknown | 15 | 19% |