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Brown Adipose Tissue in Morbidly Obese Subjects

Overview of attention for article published in PLOS ONE, February 2011
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Title
Brown Adipose Tissue in Morbidly Obese Subjects
Published in
PLOS ONE, February 2011
DOI 10.1371/journal.pone.0017247
Pubmed ID
Authors

Guy H. E. J. Vijgen, Nicole D. Bouvy, G. J. Jaap Teule, Boudewijn Brans, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt

Abstract

Cold-stimulated adaptive thermogenesis in brown adipose tissue (BAT) to increase energy expenditure is suggested as a possible therapeutic target for the treatment of obesity. We have recently shown high prevalence of BAT in adult humans, which was inversely related to body mass index (BMI) and body fat percentage (BF%), suggesting that obesity is associated with lower BAT activity. Here, we examined BAT activity in morbidly obese subjects and its role in cold-induced thermogenesis (CIT) after applying a personalized cooling protocol. We hypothesize that morbidly obese subjects show reduced BAT activity upon cold exposure.

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Mendeley readers

The data shown below were compiled from readership statistics for 270 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 1%
United States 2 <1%
Spain 2 <1%
Brazil 1 <1%
Germany 1 <1%
Switzerland 1 <1%
Canada 1 <1%
Unknown 259 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 47 17%
Researcher 42 16%
Student > Bachelor 38 14%
Student > Master 36 13%
Student > Doctoral Student 18 7%
Other 40 15%
Unknown 49 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 23%
Medicine and Dentistry 47 17%
Biochemistry, Genetics and Molecular Biology 39 14%
Nursing and Health Professions 6 2%
Immunology and Microbiology 6 2%
Other 47 17%
Unknown 64 24%