Title |
Brown Adipose Tissue in Morbidly Obese Subjects
|
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Published in |
PLOS ONE, February 2011
|
DOI | 10.1371/journal.pone.0017247 |
Pubmed ID | |
Authors |
Guy H. E. J. Vijgen, Nicole D. Bouvy, G. J. Jaap Teule, Boudewijn Brans, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt |
Abstract |
Cold-stimulated adaptive thermogenesis in brown adipose tissue (BAT) to increase energy expenditure is suggested as a possible therapeutic target for the treatment of obesity. We have recently shown high prevalence of BAT in adult humans, which was inversely related to body mass index (BMI) and body fat percentage (BF%), suggesting that obesity is associated with lower BAT activity. Here, we examined BAT activity in morbidly obese subjects and its role in cold-induced thermogenesis (CIT) after applying a personalized cooling protocol. We hypothesize that morbidly obese subjects show reduced BAT activity upon cold exposure. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 1% |
United States | 2 | <1% |
Spain | 2 | <1% |
Brazil | 1 | <1% |
Germany | 1 | <1% |
Switzerland | 1 | <1% |
Canada | 1 | <1% |
Unknown | 259 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 47 | 17% |
Researcher | 42 | 16% |
Student > Bachelor | 38 | 14% |
Student > Master | 36 | 13% |
Student > Doctoral Student | 18 | 7% |
Other | 40 | 15% |
Unknown | 49 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 61 | 23% |
Medicine and Dentistry | 47 | 17% |
Biochemistry, Genetics and Molecular Biology | 39 | 14% |
Nursing and Health Professions | 6 | 2% |
Immunology and Microbiology | 6 | 2% |
Other | 47 | 17% |
Unknown | 64 | 24% |