Report for: Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

Title	Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice
Published in	PLOS ONE, February 2011
DOI	10.1371/journal.pone.0017073
Pubmed ID	21364941
Authors	Susanna Pietropaolo, Aurélie Guilleminot, Benoît Martin, Francesca R. D'Amato, Wim E. Crusio
Abstract	No animal models of autism spectrum disorders (ASD) with good construct validity are currently available; using genetic models of pathologies characterized by ASD-like deficits, but with known causes, may be therefore a promising strategy. The Fmr1-KO mouse is an example of this approach, modeling Fragile X syndrome, a well-known genetic disorder presenting ASD symptoms. The Fmr1-KO is available on different genetic backgrounds (FVB versus C57BL/6), which may explain some of the conflicting results that have been obtained with these mutants up till now.

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France	1	100%

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Science communicators (journalists, bloggers, editors)	1	100%

Mendeley readers

The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Readers by professional status	Count	As %
Student > Ph. D. Student	35	22%
Researcher	23	14%
Student > Bachelor	18	11%
Student > Master	12	7%
Student > Doctoral Student	10	6%
Other	30	19%
Unknown	33	20%

Readers by discipline	Count	As %
Neuroscience	42	26%
Agricultural and Biological Sciences	35	22%
Biochemistry, Genetics and Molecular Biology	18	11%
Medicine and Dentistry	10	6%
Psychology	9	6%
Other	7	4%
Unknown	40	25%

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