| Title |
MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells
|
|---|---|
| Published in |
PLOS ONE, February 2011
|
| DOI | 10.1371/journal.pone.0016979 |
| Pubmed ID | |
| Authors |
Céline Sabatel, Ludovic Malvaux, Nicolas Bovy, Christophe Deroanne, Vincent Lambert, Maria-Luz Alvarez Gonzalez, Alain Colige, Jean-Marie Rakic, Agnès Noël, Joseph A. Martial, Ingrid Struman |
| Abstract |
MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that regulate gene expression at post-transcriptional level. The recent discovery of the involvement of these RNAs in the control of angiogenesis renders them very attractive in the development of new approaches for restoring the angiogenic balance. Whereas miRNA-21 has been demonstrated to be highly expressed in endothelial cells, the potential function of this miRNA in angiogenesis has never been investigated. |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| Belgium | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 146 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 46 | 30% |
| Student > Ph. D. Student | 26 | 17% |
| Student > Master | 16 | 11% |
| Student > Doctoral Student | 12 | 8% |
| Student > Bachelor | 10 | 7% |
| Other | 18 | 12% |
| Unknown | 23 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 57 | 38% |
| Biochemistry, Genetics and Molecular Biology | 30 | 20% |
| Medicine and Dentistry | 19 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Engineering | 3 | 2% |
| Other | 9 | 6% |
| Unknown | 28 | 19% |