| Title |
Immunopotentiation of Trivalent Influenza Vaccine When Given with VAX102, a Recombinant Influenza M2e Vaccine Fused to the TLR5 Ligand Flagellin
|
|---|---|
| Published in |
PLOS ONE, December 2010
|
| DOI | 10.1371/journal.pone.0014442 |
| Pubmed ID | |
| Authors |
H. Keipp Talbot, Michael T. Rock, Casey Johnson, Lynda Tussey, Uma Kavita, Anita Shanker, Alan R. Shaw, David N. Taylor |
| Abstract |
Currently controversy exists about the immunogenicity of seasonal trivalent influenza vaccine in certain populations, especially the elderly. STF2.4×M2e (VAX102) is a recombinant fusion protein that links four copies of the ectodomain of influenza virus matrix protein 2 (M2e) antigen to Salmonella typhimurium flagellin, a TLR5 ligand. The objectives of this study were to assess the feasibility of giving VAX102 and TIV in combination in an effort to achieve greater immunogenicity and to provide cross-protection. |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| India | 1 | 2% |
| Sweden | 1 | 2% |
| Unknown | 56 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 22% |
| Researcher | 12 | 20% |
| Student > Bachelor | 6 | 10% |
| Student > Master | 6 | 10% |
| Student > Postgraduate | 3 | 5% |
| Other | 8 | 13% |
| Unknown | 12 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 23% |
| Agricultural and Biological Sciences | 10 | 17% |
| Biochemistry, Genetics and Molecular Biology | 8 | 13% |
| Immunology and Microbiology | 5 | 8% |
| Veterinary Science and Veterinary Medicine | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 13 | 22% |