| Title |
Protein Kinase A Binds and Activates Heat Shock Factor 1
|
|---|---|
| Published in |
PLOS ONE, November 2010
|
| DOI | 10.1371/journal.pone.0013830 |
| Pubmed ID | |
| Authors |
Ayesha Murshid, Shiuh-Dih Chou, Thomas Prince, Yue Zhang, Ajit Bharti, Stuart K. Calderwood |
| Abstract |
Many inducible transcription factors are regulated through batteries of posttranslational modifications that couple their activity to inducing stimuli. We have studied such regulation of Heat Shock Factor 1 (HSF1), a key protein in control of the heat shock response, and a participant in carcinogenisis, neurological health and aging. As the mechanisms involved in the intracellular regulation of HSF1 in good health and its dysregulation in disease are still incomplete we are investigating the role of posttranslational modifications in such regulation. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | 1% |
| France | 1 | 1% |
| Austria | 1 | 1% |
| Brazil | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 71 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 32% |
| Researcher | 12 | 16% |
| Student > Master | 10 | 13% |
| Student > Postgraduate | 5 | 7% |
| Student > Bachelor | 4 | 5% |
| Other | 14 | 18% |
| Unknown | 7 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 45% |
| Biochemistry, Genetics and Molecular Biology | 15 | 20% |
| Medicine and Dentistry | 6 | 8% |
| Immunology and Microbiology | 2 | 3% |
| Neuroscience | 2 | 3% |
| Other | 9 | 12% |
| Unknown | 8 | 11% |