| Title |
Individual Differences in AMY1 Gene Copy Number, Salivary α-Amylase Levels, and the Perception of Oral Starch
|
|---|---|
| Published in |
PLOS ONE, October 2010
|
| DOI | 10.1371/journal.pone.0013352 |
| Pubmed ID | |
| Authors |
Abigail L. Mandel, Catherine Peyrot des Gachons, Kimberly L. Plank, Suzanne Alarcon, Paul A. S. Breslin |
| Abstract |
The digestion of dietary starch in humans is initiated by salivary α-amylase, an endo-enzyme that hydrolyzes starch into maltose, maltotriose and larger oligosaccharides. Salivary amylase accounts for 40 to 50% of protein in human saliva and rapidly alters the physical properties of starch. Importantly, the quantity and enzymatic activity of salivary amylase show significant individual variation. However, linking variation in salivary amylase levels with the oral perception of starch has proven difficult. Furthermore, the relationship between copy number variations (CNVs) in the AMY1 gene, which influence salivary amylase levels, and starch viscosity perception has not been explored. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| United Kingdom | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 295 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 1% |
| United States | 2 | <1% |
| Indonesia | 1 | <1% |
| Chile | 1 | <1% |
| Sweden | 1 | <1% |
| Portugal | 1 | <1% |
| Nigeria | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 284 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 67 | 23% |
| Student > Ph. D. Student | 41 | 14% |
| Researcher | 36 | 12% |
| Student > Master | 25 | 8% |
| Student > Doctoral Student | 14 | 5% |
| Other | 34 | 12% |
| Unknown | 78 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 64 | 22% |
| Biochemistry, Genetics and Molecular Biology | 36 | 12% |
| Medicine and Dentistry | 17 | 6% |
| Engineering | 14 | 5% |
| Nursing and Health Professions | 10 | 3% |
| Other | 62 | 21% |
| Unknown | 92 | 31% |