| Title |
Reduced Satellite Cell Numbers and Myogenic Capacity in Aging Can Be Alleviated by Endurance Exercise
|
|---|---|
| Published in |
PLOS ONE, October 2010
|
| DOI | 10.1371/journal.pone.0013307 |
| Pubmed ID | |
| Authors |
Gabi Shefer, Gat Rauner, Zipora Yablonka-Reuveni, Dafna Benayahu |
| Abstract |
Muscle regeneration depends on satellite cells, myogenic stem cells that reside on the myofiber surface. Reduced numbers and/or decreased myogenic aptitude of these cells may impede proper maintenance and contribute to the age-associated decline in muscle mass and repair capacity. Endurance exercise was shown to improve muscle performance; however, the direct impact on satellite cells in aging was not yet thoroughly determined. Here, we focused on characterizing the effect of moderate-intensity endurance exercise on satellite cell, as possible means to attenuate adverse effects of aging. Young and old rats of both genders underwent 13 weeks of treadmill-running or remained sedentary. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 38% |
| Côte d'Ivoire | 1 | 13% |
| United States | 1 | 13% |
| Norway | 1 | 13% |
| Unknown | 2 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 75% |
| Scientists | 1 | 13% |
| Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 200 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 3% |
| United Kingdom | 4 | 2% |
| Brazil | 3 | 2% |
| Denmark | 1 | <1% |
| Japan | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 184 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 17% |
| Researcher | 33 | 17% |
| Student > Master | 28 | 14% |
| Student > Bachelor | 22 | 11% |
| Professor > Associate Professor | 12 | 6% |
| Other | 41 | 21% |
| Unknown | 30 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 49 | 25% |
| Biochemistry, Genetics and Molecular Biology | 36 | 18% |
| Medicine and Dentistry | 32 | 16% |
| Sports and Recreations | 19 | 10% |
| Neuroscience | 5 | 3% |
| Other | 21 | 11% |
| Unknown | 38 | 19% |