| Title |
Minocycline Synergizes with N-Acetylcysteine and Improves Cognition and Memory Following Traumatic Brain Injury in Rats
|
|---|---|
| Published in |
PLOS ONE, August 2010
|
| DOI | 10.1371/journal.pone.0012490 |
| Pubmed ID | |
| Authors |
Samah G. Abdel Baki, Ben Schwab, Margalit Haber, André A. Fenton, Peter J. Bergold |
| Abstract |
There are no drugs presently available to treat traumatic brain injury (TBI). A variety of single drugs have failed clinical trials suggesting a role for drug combinations. Drug combinations acting synergistically often provide the greatest combination of potency and safety. The drugs examined (minocycline (MINO), N-acetylcysteine (NAC), simvastatin, cyclosporine A, and progesterone) had FDA-approval for uses other than TBI and limited brain injury in experimental TBI models. |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 4% |
| Iran, Islamic Republic of | 1 | 1% |
| Unknown | 87 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 16% |
| Researcher | 13 | 14% |
| Student > Bachelor | 10 | 11% |
| Student > Master | 9 | 10% |
| Professor > Associate Professor | 8 | 9% |
| Other | 23 | 25% |
| Unknown | 14 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 32% |
| Neuroscience | 13 | 14% |
| Agricultural and Biological Sciences | 11 | 12% |
| Psychology | 6 | 7% |
| Engineering | 3 | 3% |
| Other | 10 | 11% |
| Unknown | 20 | 22% |