| Title |
The Protease Inhibitor Alpha-2-Macroglobuline-Like-1 Is the p170 Antigen Recognized by Paraneoplastic Pemphigus Autoantibodies in Human
|
|---|---|
| Published in |
PLOS ONE, August 2010
|
| DOI | 10.1371/journal.pone.0012250 |
| Pubmed ID | |
| Authors |
Isabelle Schepens, Fabienne Jaunin, Nadja Begre, Ursula Läderach, Katrin Marcus, Takashi Hashimoto, Bertrand Favre, Luca Borradori |
| Abstract |
Paraneoplastic pemphigus (PNP) is a devastating autoimmune blistering disease, involving mucocutaneous and internal organs, and associated with underlying neoplasms. PNP is characterized by the production of autoantibodies targeting proteins of the plakin and cadherin families involved in maintenance of cell architecture and tissue cohesion. Nevertheless, the identity of an antigen of Mr 170,000 (p170), thought to be critical in PNP pathogenesis, has remained unknown. |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 6 | 17% |
| Researcher | 4 | 11% |
| Student > Doctoral Student | 4 | 11% |
| Student > Master | 4 | 11% |
| Student > Bachelor | 2 | 6% |
| Other | 7 | 19% |
| Unknown | 9 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 39% |
| Immunology and Microbiology | 4 | 11% |
| Agricultural and Biological Sciences | 3 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Environmental Science | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 10 | 28% |