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An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis

Overview of attention for article published in PLOS ONE, June 2010
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Title
An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis
Published in
PLOS ONE, June 2010
DOI 10.1371/journal.pone.0010993
Pubmed ID
Authors

Ge Jin, Hameem I. Kawsar, Stanley A. Hirsch, Chun Zeng, Xun Jia, Zhimin Feng, Santosh K. Ghosh, Qing Yin Zheng, Aimin Zhou, Thomas M. McIntyre, Aaron Weinberg

Abstract

Tumor-associated macrophages (TAMs) constitute a significant part of infiltrating inflammatory cells that are frequently correlated with progression and poor prognosis of a variety of cancers. Tumor cell-produced human beta-defensin-3 (hBD-3) has been associated with TAM trafficking in oral cancer; however, its involvement in tumor-related inflammatory processes remains largely unknown.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Sweden 1 1%
France 1 1%
Unknown 94 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 22%
Researcher 20 21%
Student > Bachelor 14 14%
Student > Master 11 11%
Other 8 8%
Other 9 9%
Unknown 14 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 33%
Biochemistry, Genetics and Molecular Biology 16 16%
Medicine and Dentistry 10 10%
Immunology and Microbiology 7 7%
Engineering 5 5%
Other 8 8%
Unknown 19 20%