| Title |
Disrupted Functional Connectivity with Dopaminergic Midbrain in Cocaine Abusers
|
|---|---|
| Published in |
PLOS ONE, May 2010
|
| DOI | 10.1371/journal.pone.0010815 |
| Pubmed ID | |
| Authors |
Dardo Tomasi, Nora D. Volkow, Ruiliang Wang, Jean H. Carrillo, Thomas Maloney, Nelly Alia-Klein, Patricia A. Woicik, Frank Telang, Rita Z. Goldstein |
| Abstract |
Chronic cocaine use is associated with disrupted dopaminergic neurotransmission but how this disruption affects overall brain function (other than reward/motivation) is yet to be fully investigated. Here we test the hypothesis that cocaine addicted subjects will have disrupted functional connectivity between the midbrain (where dopamine neurons are located) and cortical and subcortical brain regions during the performance of a sustained attention task. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 5% |
| Brazil | 1 | <1% |
| Sweden | 1 | <1% |
| South Africa | 1 | <1% |
| France | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| China | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 140 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 32 | 21% |
| Student > Ph. D. Student | 31 | 20% |
| Student > Master | 17 | 11% |
| Student > Doctoral Student | 15 | 10% |
| Student > Bachelor | 12 | 8% |
| Other | 29 | 19% |
| Unknown | 19 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 45 | 29% |
| Neuroscience | 26 | 17% |
| Agricultural and Biological Sciences | 22 | 14% |
| Medicine and Dentistry | 12 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 14 | 9% |
| Unknown | 33 | 21% |