| Title |
Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations
|
|---|---|
| Published in |
PLOS ONE, May 2010
|
| DOI | 10.1371/journal.pone.0010680 |
| Pubmed ID | |
| Authors |
Alberto Diaz de Leon, Jennifer T. Cronkhite, Anna-Luise A. Katzenstein, J. David Godwin, Ganesh Raghu, Craig S. Glazer, Randall L. Rosenblatt, Carlos E. Girod, Edward R. Garrity, Chao Xing, Christine Kim Garcia |
| Abstract |
Telomerase is an enzyme that catalyzes the addition of nucleotides on the ends of chromosomes. Rare loss of function mutations in the gene that encodes the protein component of telomerase (TERT) have been described in patients with idiopathic pulmonary fibrosis (IPF). Here we examine the telomere lengths and pulmonary fibrosis phenotype seen in multiple kindreds with heterozygous TERT mutations. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Guinea | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 183 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 3% |
| South Africa | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| India | 1 | <1% |
| Unknown | 174 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 16% |
| Researcher | 27 | 15% |
| Other | 17 | 9% |
| Student > Bachelor | 16 | 9% |
| Student > Master | 13 | 7% |
| Other | 45 | 25% |
| Unknown | 36 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 61 | 33% |
| Agricultural and Biological Sciences | 32 | 17% |
| Biochemistry, Genetics and Molecular Biology | 20 | 11% |
| Immunology and Microbiology | 5 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Other | 17 | 9% |
| Unknown | 43 | 23% |