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High-Content, Image-Based Screening for Drug Targets in Yeast

Overview of attention for article published in PLOS ONE, April 2010
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Title
High-Content, Image-Based Screening for Drug Targets in Yeast
Published in
PLOS ONE, April 2010
DOI 10.1371/journal.pone.0010177
Pubmed ID
Authors

Shinsuke Ohnuki, Satomi Oka, Satoru Nogami, Yoshikazu Ohya

Abstract

Drug discovery and development are predicated on elucidation of the potential mechanisms of action and cellular targets of candidate chemical compounds. Recent advances in high-content imaging techniques allow simultaneous analysis of a range of cellular events. In this study, we propose a novel strategy to identify drug targets by combining genetic screening and high-content imaging in yeast.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 2%
Germany 1 2%
Italy 1 2%
New Zealand 1 2%
Spain 1 2%
Luxembourg 1 2%
Unknown 58 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 23%
Student > Ph. D. Student 14 22%
Student > Master 9 14%
Other 5 8%
Student > Bachelor 4 6%
Other 9 14%
Unknown 8 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 56%
Biochemistry, Genetics and Molecular Biology 10 16%
Engineering 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Physics and Astronomy 1 2%
Other 0 0%
Unknown 8 13%