Title |
Clinical Utility of a Commercial LAM-ELISA Assay for TB Diagnosis in HIV-Infected Patients Using Urine and Sputum Samples
|
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Published in |
PLOS ONE, March 2010
|
DOI | 10.1371/journal.pone.0009848 |
Pubmed ID | |
Authors |
Keertan Dheda, Virginia Davids, Laura Lenders, Teri Roberts, Richard Meldau, Daphne Ling, Laurence Brunet, Richard van Zyl Smit, Jonathan Peter, Clare Green, Motasim Badri, Leonardo Sechi, Surendra Sharma, Michael Hoelscher, Rodney Dawson, Andrew Whitelaw, Jonathan Blackburn, Madhukar Pai, Alimuddin Zumla |
Abstract |
The accurate diagnosis of TB in HIV-infected patients, particularly with advanced immunosuppression, is difficult. Recent studies indicate that a lipoarabinomannan (LAM) assay (Clearview-TB(R)-ELISA) may have some utility for the diagnosis of TB in HIV-infected patients; however, the precise subgroup that may benefit from this technology requires clarification. The utility of LAM in sputum samples has, hitherto, not been evaluated. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 75% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 3 | 2% |
Austria | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
Denmark | 1 | <1% |
United States | 1 | <1% |
Unknown | 192 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 43 | 22% |
Student > Master | 32 | 16% |
Student > Ph. D. Student | 31 | 16% |
Student > Bachelor | 19 | 10% |
Student > Postgraduate | 15 | 8% |
Other | 34 | 17% |
Unknown | 26 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 72 | 36% |
Agricultural and Biological Sciences | 32 | 16% |
Biochemistry, Genetics and Molecular Biology | 17 | 9% |
Immunology and Microbiology | 14 | 7% |
Chemistry | 9 | 5% |
Other | 25 | 13% |
Unknown | 31 | 16% |