| Title |
First Qualification Study of Serum Biomarkers as Indicators of Total Body Burden of Osteoarthritis
|
|---|---|
| Published in |
PLOS ONE, March 2010
|
| DOI | 10.1371/journal.pone.0009739 |
| Pubmed ID | |
| Authors |
Virginia B. Kraus, Thomas B. Kepler, Thomas Stabler, Jordan Renner, Joanne Jordan |
| Abstract |
Osteoarthritis (OA) is a debilitating chronic multijoint disease of global proportions. OA presence and severity is usually documented by x-ray imaging but whole body imaging is impractical due to radiation exposure, time and cost. Systemic (serum or urine) biomarkers offer a potential alternative method of quantifying total body burden of disease but no OA-related biomarker has ever been stringently qualified to determine the feasibility of this approach. The goal of this study was to evaluate the ability of three OA-related biomarkers to predict various forms or subspecies of OA and total body burden of disease. |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Italy | 1 | 2% |
| Norway | 1 | 2% |
| Unknown | 62 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 26% |
| Student > Ph. D. Student | 9 | 14% |
| Other | 6 | 9% |
| Student > Master | 6 | 9% |
| Professor | 4 | 6% |
| Other | 14 | 22% |
| Unknown | 9 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 35% |
| Agricultural and Biological Sciences | 8 | 12% |
| Nursing and Health Professions | 6 | 9% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Engineering | 3 | 5% |
| Other | 5 | 8% |
| Unknown | 15 | 23% |