Title |
Regulation of Proapoptotic Mammalian ste20–Like Kinase MST2 by the IGF1-Akt Pathway
|
---|---|
Published in |
PLOS ONE, March 2010
|
DOI | 10.1371/journal.pone.0009616 |
Pubmed ID | |
Authors |
Donghwa Kim, Shaokun Shu, Marc D. Coppola, Satoshi Kaneko, Zeng-qiang Yuan, Jin Q. Cheng |
Abstract |
Hippo, a Drosophila serine/threonine kinase, promotes apoptosis and restricts cell growth and proliferation. Its mammalian homolog MST2 has been shown to play similar role and be regulated by Raf-1 via a kinase-independent mechanism and by RASSF family proteins through forming complex with MST2. However, regulation of MST2 by cell survival signal remains largely unknown. |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 45 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 26% |
Student > Ph. D. Student | 10 | 22% |
Student > Bachelor | 8 | 17% |
Professor > Associate Professor | 5 | 11% |
Student > Master | 5 | 11% |
Other | 4 | 9% |
Unknown | 2 | 4% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 57% |
Biochemistry, Genetics and Molecular Biology | 9 | 20% |
Medicine and Dentistry | 6 | 13% |
Neuroscience | 2 | 4% |
Unknown | 3 | 7% |