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Regulation of Proapoptotic Mammalian ste20–Like Kinase MST2 by the IGF1-Akt Pathway

Overview of attention for article published in PLOS ONE, March 2010
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Title
Regulation of Proapoptotic Mammalian ste20–Like Kinase MST2 by the IGF1-Akt Pathway
Published in
PLOS ONE, March 2010
DOI 10.1371/journal.pone.0009616
Pubmed ID
Authors

Donghwa Kim, Shaokun Shu, Marc D. Coppola, Satoshi Kaneko, Zeng-qiang Yuan, Jin Q. Cheng

Abstract

Hippo, a Drosophila serine/threonine kinase, promotes apoptosis and restricts cell growth and proliferation. Its mammalian homolog MST2 has been shown to play similar role and be regulated by Raf-1 via a kinase-independent mechanism and by RASSF family proteins through forming complex with MST2. However, regulation of MST2 by cell survival signal remains largely unknown.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 26%
Student > Ph. D. Student 10 22%
Student > Bachelor 8 17%
Professor > Associate Professor 5 11%
Student > Master 5 11%
Other 4 9%
Unknown 2 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 57%
Biochemistry, Genetics and Molecular Biology 9 20%
Medicine and Dentistry 6 13%
Neuroscience 2 4%
Unknown 3 7%