| Title |
Upregulation of SOCS-3 and PIAS-3 Impairs IL-12-Mediated Interferon-Gamma Response in CD56+ T Cells in HCV-Infected Heroin Users
|
|---|---|
| Published in |
PLOS ONE, March 2010
|
| DOI | 10.1371/journal.pone.0009602 |
| Pubmed ID | |
| Authors |
Li Ye, Xu Wang, David S. Metzger, Eric Riedel, Luis J. Montaner, Wenzhe Ho |
| Abstract |
CD56(+) T cells are abundant in liver and play an important role in host innate immunity against viral infections, including hepatitis C virus (HCV) infection, a common infection among heroin abusers. We thus investigated the in vivo impact of heroin use or heroin use plus HCV infection on the CD56(+) T cell frequency and function. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 4% |
| United Kingdom | 1 | 4% |
| Unknown | 26 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 29% |
| Researcher | 6 | 21% |
| Professor | 4 | 14% |
| Student > Master | 3 | 11% |
| Lecturer | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 4 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 36% |
| Immunology and Microbiology | 3 | 11% |
| Psychology | 3 | 11% |
| Medicine and Dentistry | 3 | 11% |
| Business, Management and Accounting | 1 | 4% |
| Other | 4 | 14% |
| Unknown | 4 | 14% |