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CD28 Down-Regulation on Circulating CD4 T-Cells Is Associated with Poor Prognoses of Patients with Idiopathic Pulmonary Fibrosis

Overview of attention for article published in PLOS ONE, January 2010
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Title
CD28 Down-Regulation on Circulating CD4 T-Cells Is Associated with Poor Prognoses of Patients with Idiopathic Pulmonary Fibrosis
Published in
PLOS ONE, January 2010
DOI 10.1371/journal.pone.0008959
Pubmed ID
Authors

Syed R. Gilani, Louis J. Vuga, Kathleen O. Lindell, Kevin F. Gibson, Jianmin Xue, Naftali Kaminski, Vincent G. Valentine, Emily K. Lindsay, M. Patricia George, Chad Steele, Steven R. Duncan

Abstract

Although the etiology of idiopathic pulmonary fibrosis (IPF) remains perplexing, adaptive immune activation is evident among many afflicted patients. Repeated cycles of antigen-induced proliferation cause T-cells to lose surface expression of CD28, and we hypothesized this process might also occur in IPF.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
Unknown 77 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 27 35%
Student > Ph. D. Student 11 14%
Student > Bachelor 8 10%
Student > Master 6 8%
Professor > Associate Professor 4 5%
Other 10 13%
Unknown 12 15%
Readers by discipline Count As %
Medicine and Dentistry 30 38%
Agricultural and Biological Sciences 8 10%
Immunology and Microbiology 6 8%
Biochemistry, Genetics and Molecular Biology 4 5%
Nursing and Health Professions 4 5%
Other 10 13%
Unknown 16 21%