Title |
CD28 Down-Regulation on Circulating CD4 T-Cells Is Associated with Poor Prognoses of Patients with Idiopathic Pulmonary Fibrosis
|
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Published in |
PLOS ONE, January 2010
|
DOI | 10.1371/journal.pone.0008959 |
Pubmed ID | |
Authors |
Syed R. Gilani, Louis J. Vuga, Kathleen O. Lindell, Kevin F. Gibson, Jianmin Xue, Naftali Kaminski, Vincent G. Valentine, Emily K. Lindsay, M. Patricia George, Chad Steele, Steven R. Duncan |
Abstract |
Although the etiology of idiopathic pulmonary fibrosis (IPF) remains perplexing, adaptive immune activation is evident among many afflicted patients. Repeated cycles of antigen-induced proliferation cause T-cells to lose surface expression of CD28, and we hypothesized this process might also occur in IPF. |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 1% |
Unknown | 77 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 27 | 35% |
Student > Ph. D. Student | 11 | 14% |
Student > Bachelor | 8 | 10% |
Student > Master | 6 | 8% |
Professor > Associate Professor | 4 | 5% |
Other | 10 | 13% |
Unknown | 12 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 38% |
Agricultural and Biological Sciences | 8 | 10% |
Immunology and Microbiology | 6 | 8% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Nursing and Health Professions | 4 | 5% |
Other | 10 | 13% |
Unknown | 16 | 21% |