| Title |
Cytomegalovirus-Specific T Cells Persist at Very High Levels during Long-Term Antiretroviral Treatment of HIV Disease
|
|---|---|
| Published in |
PLOS ONE, January 2010
|
| DOI | 10.1371/journal.pone.0008886 |
| Pubmed ID | |
| Authors |
David M. Naeger, Jeffrey N. Martin, Elizabeth Sinclair, Peter W. Hunt, David R. Bangsberg, Frederick Hecht, Priscilla Hsue, Joseph M. McCune, Steven G. Deeks |
| Abstract |
In healthy, HIV seronegative, CMV seropositive adults, a large proportion of T cells are CMV-specific. High-level CMV-specific T cell responses are associated with accelerated immunologic aging ("immunosenesence") in the elderly population. The impact of untreated and treated HIV infection on the frequency of these cells remains undefined. |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | <1% |
| United Kingdom | 1 | <1% |
| Belgium | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 110 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 19% |
| Researcher | 19 | 17% |
| Student > Master | 14 | 12% |
| Student > Postgraduate | 12 | 10% |
| Student > Bachelor | 10 | 9% |
| Other | 26 | 23% |
| Unknown | 12 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 37% |
| Agricultural and Biological Sciences | 22 | 19% |
| Immunology and Microbiology | 20 | 17% |
| Biochemistry, Genetics and Molecular Biology | 8 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 5 | 4% |
| Unknown | 15 | 13% |