| Title |
Glycemic Control Promotes Pancreatic Beta-Cell Regeneration in Streptozotocin-Induced Diabetic Mice
|
|---|---|
| Published in |
PLOS ONE, January 2010
|
| DOI | 10.1371/journal.pone.0008749 |
| Pubmed ID | |
| Authors |
Eric J. Grossman, David D. Lee, Jing Tao, Raphael A. Wilson, Soo-Young Park, Graeme I. Bell, Anita S. Chong |
| Abstract |
Pancreatic beta-cells proliferate following administration of the beta-cell toxin streptozotocin. Defining the conditions that promote beta-cell proliferation could benefit patients with diabetes. We have investigated the effect of insulin treatment on pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice, and, in addition, report on a new approach to quantify beta-cell regeneration in vivo. |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 1% |
| India | 1 | 1% |
| Argentina | 1 | 1% |
| United States | 1 | 1% |
| Jordan | 1 | 1% |
| Unknown | 95 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 24% |
| Researcher | 14 | 14% |
| Student > Master | 13 | 13% |
| Student > Bachelor | 8 | 8% |
| Other | 8 | 8% |
| Other | 20 | 20% |
| Unknown | 13 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 39 | 39% |
| Medicine and Dentistry | 17 | 17% |
| Biochemistry, Genetics and Molecular Biology | 12 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 7% |
| Immunology and Microbiology | 4 | 4% |
| Other | 8 | 8% |
| Unknown | 13 | 13% |