Title |
Estrogen Receptor Alpha as a Key Target of Red Wine Polyphenols Action on the Endothelium
|
---|---|
Published in |
PLOS ONE, January 2010
|
DOI | 10.1371/journal.pone.0008554 |
Pubmed ID | |
Authors |
Matthieu Chalopin, Angela Tesse, Maria Carmen Martínez, Didier Rognan, Jean-François Arnal, Ramaroson Andriantsitohaina |
Abstract |
A greater reduction in cardiovascular risk and vascular protection associated with diet rich in polyphenols are generally accepted; however, the molecular targets for polyphenols effects remain unknown. Meanwhile evidences in the literature have enlightened, not only structural similarities between estrogens and polyphenols known as phytoestrogens, but also in their vascular effects. We hypothesized that alpha isoform of estrogen receptor (ERalpha) could be involved in the transduction of the vascular benefits of polyphenols. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 50% |
Australia | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 2% |
Canada | 2 | 2% |
Italy | 1 | 1% |
United Kingdom | 1 | 1% |
Belgium | 1 | 1% |
Unknown | 85 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 20% |
Student > Ph. D. Student | 17 | 18% |
Other | 10 | 11% |
Professor > Associate Professor | 8 | 9% |
Student > Bachelor | 5 | 5% |
Other | 17 | 18% |
Unknown | 17 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 31 | 34% |
Biochemistry, Genetics and Molecular Biology | 9 | 10% |
Medicine and Dentistry | 9 | 10% |
Neuroscience | 4 | 4% |
Chemistry | 4 | 4% |
Other | 12 | 13% |
Unknown | 23 | 25% |