Title |
Mst1-FoxO Signaling Protects Naïve T Lymphocytes from Cellular Oxidative Stress in Mice
|
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Published in |
PLOS ONE, November 2009
|
DOI | 10.1371/journal.pone.0008011 |
Pubmed ID | |
Authors |
Juhyun Choi, Sangphil Oh, Dongjun Lee, Hyun Jung Oh, Jik Young Park, Sean Bong Lee, Dae-Sik Lim |
Abstract |
The Ste-20 family kinase Hippo restricts cell proliferation and promotes apoptosis for proper organ development in Drosophila. In C. elegans, Hippo homolog also regulates longevity. The mammalian Ste20-like protein kinase, Mst1, plays a role in apoptosis induced by various types of apoptotic stress. Mst1 also regulates peripheral naïve T cell trafficking and proliferation in mice. However, its functions in mammals are not fully understood. |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
United States | 1 | 1% |
Poland | 1 | 1% |
China | 1 | 1% |
Unknown | 66 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 24% |
Researcher | 13 | 19% |
Student > Master | 8 | 11% |
Professor > Associate Professor | 5 | 7% |
Professor | 4 | 6% |
Other | 11 | 16% |
Unknown | 12 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 37% |
Medicine and Dentistry | 10 | 14% |
Biochemistry, Genetics and Molecular Biology | 9 | 13% |
Immunology and Microbiology | 5 | 7% |
Engineering | 2 | 3% |
Other | 1 | 1% |
Unknown | 17 | 24% |