| Title |
miR-155 Inhibition Sensitizes CD4+ Th Cells for TREG Mediated Suppression
|
|---|---|
| Published in |
PLOS ONE, September 2009
|
| DOI | 10.1371/journal.pone.0007158 |
| Pubmed ID | |
| Authors |
Heiko F. Stahl, Tanja Fauti, Nina Ullrich, Tobias Bopp, Jan Kubach, Werner Rust, Paul Labhart, Vassili Alexiadis, Christian Becker, Mathias Hafner, Andreas Weith, Martin C. Lenter, Helmut Jonuleit, Edgar Schmitt, Detlev Mennerich |
| Abstract |
In humans and mice naturally occurring CD4(+)CD25(+) regulatory T cells (nTregs) are a thymus-derived subset of T cells, crucial for the maintenance of peripheral tolerance by controlling not only potentially autoreactive T cells but virtually all cells of the adaptive and innate immune system. Recent work using Dicer-deficient mice irrevocably demonstrated the importance of miRNAs for nTreg cell-mediated tolerance. |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Italy | 1 | 1% |
| Germany | 1 | 1% |
| China | 1 | 1% |
| Sweden | 1 | 1% |
| Unknown | 80 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 25 | 29% |
| Student > Ph. D. Student | 18 | 21% |
| Professor > Associate Professor | 7 | 8% |
| Student > Bachelor | 7 | 8% |
| Student > Master | 5 | 6% |
| Other | 13 | 15% |
| Unknown | 12 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 44% |
| Medicine and Dentistry | 16 | 18% |
| Immunology and Microbiology | 7 | 8% |
| Biochemistry, Genetics and Molecular Biology | 6 | 7% |
| Engineering | 3 | 3% |
| Other | 4 | 5% |
| Unknown | 13 | 15% |