| Title |
Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo
|
|---|---|
| Published in |
PLOS ONE, August 2009
|
| DOI | 10.1371/journal.pone.0006839 |
| Pubmed ID | |
| Authors |
Polloneal Jymmiel R. Ocbina, Miquel Tuson, Kathryn V. Anderson |
| Abstract |
Sonic hedgehog (Shh) signaling in the mouse requires the microtubule-based organelle, the primary cilium. The primary cilium is assembled and maintained through the process of intraflagellar transport (IFT) and the response to Shh is blocked in mouse mutants that lack proteins required for IFT. Although the phenotypes of mouse IFT mutants do not overlap with phenotypes of known Wnt pathway mutants, recent studies report data suggesting that the primary cilium modulates responses to Wnt signals. |
Mendeley readers
The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 4% |
| United Kingdom | 1 | <1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 149 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 49 | 31% |
| Researcher | 30 | 19% |
| Student > Master | 12 | 8% |
| Student > Bachelor | 10 | 6% |
| Professor > Associate Professor | 9 | 6% |
| Other | 27 | 17% |
| Unknown | 21 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 73 | 46% |
| Biochemistry, Genetics and Molecular Biology | 39 | 25% |
| Medicine and Dentistry | 9 | 6% |
| Neuroscience | 9 | 6% |
| Engineering | 2 | 1% |
| Other | 5 | 3% |
| Unknown | 21 | 13% |