| Title |
Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human
|
|---|---|
| Published in |
PLOS ONE, August 2009
|
| DOI | 10.1371/journal.pone.0006796 |
| Pubmed ID | |
| Authors |
Maryam Rakhshandehroo, Guido Hooiveld, Michael Müller, Sander Kersten |
| Abstract |
Studies in mice have shown that PPARalpha is an important regulator of hepatic lipid metabolism and the acute phase response. However, little information is available on the role of PPARalpha in human liver. Here we set out to compare the function of PPARalpha in mouse and human hepatocytes via analysis of target gene regulation. |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Germany | 1 | <1% |
| India | 1 | <1% |
| Ireland | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 181 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 29% |
| Researcher | 30 | 16% |
| Student > Master | 27 | 14% |
| Student > Bachelor | 19 | 10% |
| Other | 9 | 5% |
| Other | 30 | 16% |
| Unknown | 20 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 70 | 37% |
| Biochemistry, Genetics and Molecular Biology | 41 | 22% |
| Medicine and Dentistry | 26 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 5% |
| Immunology and Microbiology | 4 | 2% |
| Other | 15 | 8% |
| Unknown | 25 | 13% |