| Title |
Loss of GATA4 and GATA6 Expression Specifies Ovarian Cancer Histological Subtypes and Precedes Neoplastic Transformation of Ovarian Surface Epithelia
|
|---|---|
| Published in |
PLOS ONE, July 2009
|
| DOI | 10.1371/journal.pone.0006454 |
| Pubmed ID | |
| Authors |
Kathy Qi Cai, Corrado Caslini, Callinice D. Capo-chichi, Carolyn Slater, Elizabeth R. Smith, Hong Wu, Andres J. Klein-Szanto, Andrew K. Godwin, Xiang-Xi Xu |
| Abstract |
The family of zinc finger-containing GATA transcription factors plays critical roles in cell lineage specification during early embryonic development and organ formation. GATA4 and GATA6 were found to be frequently lost in ovarian cancer, and the loss is proposed to account for dedifferentiation of the cancer cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 39 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 31% |
| Researcher | 10 | 26% |
| Professor > Associate Professor | 4 | 10% |
| Student > Doctoral Student | 3 | 8% |
| Student > Master | 3 | 8% |
| Other | 6 | 15% |
| Unknown | 1 | 3% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 41% |
| Biochemistry, Genetics and Molecular Biology | 8 | 21% |
| Medicine and Dentistry | 8 | 21% |
| Veterinary Science and Veterinary Medicine | 2 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Other | 4 | 10% |