Title |
Neural Differentiation of Embryonic Stem Cells In Vitro: A Road Map to Neurogenesis in the Embryo
|
---|---|
Published in |
PLOS ONE, July 2009
|
DOI | 10.1371/journal.pone.0006286 |
Pubmed ID | |
Authors |
Elsa Abranches, Margarida Silva, Laurent Pradier, Herbert Schulz, Oliver Hummel, Domingos Henrique, Evguenia Bekman |
Abstract |
The in vitro generation of neurons from embryonic stem (ES) cells is a promising approach to produce cells suitable for neural tissue repair and cell-based replacement therapies of the nervous system. Available methods to promote ES cell differentiation towards neural lineages attempt to replicate, in different ways, the multistep process of embryonic neural development. However, to achieve this aim in an efficient and reproducible way, a better knowledge of the cellular and molecular events that are involved in the process, from the initial specification of neuroepithelial progenitors to their terminal differentiation into neurons and glial cells, is required. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 15 | 3% |
United States | 8 | 2% |
Germany | 3 | <1% |
Portugal | 3 | <1% |
Denmark | 2 | <1% |
India | 2 | <1% |
Chile | 1 | <1% |
Austria | 1 | <1% |
Australia | 1 | <1% |
Other | 9 | 2% |
Unknown | 457 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 143 | 28% |
Researcher | 124 | 25% |
Student > Master | 70 | 14% |
Student > Bachelor | 37 | 7% |
Student > Doctoral Student | 21 | 4% |
Other | 69 | 14% |
Unknown | 38 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 265 | 53% |
Biochemistry, Genetics and Molecular Biology | 89 | 18% |
Medicine and Dentistry | 35 | 7% |
Neuroscience | 31 | 6% |
Engineering | 20 | 4% |
Other | 18 | 4% |
Unknown | 44 | 9% |