Title |
Heritable and Lineage-Specific Gene Knockdown in Zebrafish Embryo
|
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Published in |
PLOS ONE, July 2009
|
DOI | 10.1371/journal.pone.0006125 |
Pubmed ID | |
Authors |
Mei Dong, Yan-Fang Fu, Ting-Ting Du, Chang-Bin Jing, Chun-Tang Fu, Yi Chen, Yi Jin, Min Deng, Ting Xi Liu |
Abstract |
Reduced expression of developmentally important genes and tumor suppressors due to haploinsufficiency or epigenetic suppression has been shown to contribute to the pathogenesis of various malignancies. However, methodology that allows spatio-temporally knockdown of gene expression in various model organisms such as zebrafish has not been well established, which largely limits the potential of zebrafish as a vertebrate model of human malignant disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 4% |
Germany | 1 | <1% |
Netherlands | 1 | <1% |
Sweden | 1 | <1% |
Portugal | 1 | <1% |
United Kingdom | 1 | <1% |
India | 1 | <1% |
Spain | 1 | <1% |
Mexico | 1 | <1% |
Other | 0 | 0% |
Unknown | 100 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 31 | 28% |
Researcher | 28 | 25% |
Professor > Associate Professor | 12 | 11% |
Student > Master | 12 | 11% |
Professor | 8 | 7% |
Other | 14 | 13% |
Unknown | 7 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 68 | 61% |
Biochemistry, Genetics and Molecular Biology | 20 | 18% |
Medicine and Dentistry | 4 | 4% |
Neuroscience | 4 | 4% |
Materials Science | 2 | 2% |
Other | 4 | 4% |
Unknown | 10 | 9% |