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Dopamine Transporters in Striatum Correlate with Deactivation in the Default Mode Network during Visuospatial Attention

Overview of attention for article published in PLOS ONE, June 2009
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Title
Dopamine Transporters in Striatum Correlate with Deactivation in the Default Mode Network during Visuospatial Attention
Published in
PLOS ONE, June 2009
DOI 10.1371/journal.pone.0006102
Pubmed ID
Authors

Dardo Tomasi, Nora D. Volkow, Ruiliang Wang, Frank Telang, Gene-Jack Wang, Linda Chang, Thomas Ernst, Joanna S. Fowler

Abstract

Dopamine and dopamine transporters (DAT, which regulate extracellular dopamine in the brain) are implicated in the modulation of attention but their specific roles are not well understood. Here we hypothesized that dopamine modulates attention by facilitation of brain deactivation in the default mode network (DMN). Thus, higher striatal DAT levels, which would result in an enhanced clearance of dopamine and hence weaker dopamine signals, would be associated to lower deactivation in the DMN during an attention task.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 3%
Netherlands 2 1%
Germany 2 1%
Spain 2 1%
Switzerland 1 <1%
South Africa 1 <1%
Chile 1 <1%
Japan 1 <1%
Italy 1 <1%
Other 0 0%
Unknown 168 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 46 25%
Student > Ph. D. Student 45 24%
Student > Master 16 9%
Student > Doctoral Student 13 7%
Student > Bachelor 13 7%
Other 36 19%
Unknown 16 9%
Readers by discipline Count As %
Psychology 56 30%
Medicine and Dentistry 31 17%
Neuroscience 25 14%
Agricultural and Biological Sciences 19 10%
Nursing and Health Professions 5 3%
Other 16 9%
Unknown 33 18%