Title |
Origin of Saxitoxin Biosynthetic Genes in Cyanobacteria
|
---|---|
Published in |
PLOS ONE, June 2009
|
DOI | 10.1371/journal.pone.0005758 |
Pubmed ID | |
Authors |
Ahmed Moustafa, Jeannette E. Loram, Jeremiah D. Hackett, Donald M. Anderson, F. Gerald Plumley, Debashish Bhattacharya |
Abstract |
Paralytic shellfish poisoning (PSP) is a potentially fatal syndrome associated with the consumption of shellfish that have accumulated saxitoxin (STX). STX is produced by microscopic marine dinoflagellate algae. Little is known about the origin and spread of saxitoxin genes in these under-studied eukaryotes. Fortuitously, some freshwater cyanobacteria also produce STX, providing an ideal model for studying its biosynthesis. Here we focus on saxitoxin-producing cyanobacteria and their non-toxic sisters to elucidate the origin of genes involved in the putative STX biosynthetic pathway. |
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