| Title |
Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H37Rv and the β-Ketoacyl-ACP Synthase mtFabH
|
|---|---|
| Published in |
PLOS ONE, May 2009
|
| DOI | 10.1371/journal.pone.0005617 |
| Pubmed ID | |
| Authors |
Qosay Al-Balas, Nahoum G. Anthony, Bilal Al-Jaidi, Amani Alnimr, Grainne Abbott, Alistair K. Brown, Rebecca C. Taylor, Gurdyal S. Besra, Timothy D. McHugh, Stephen H. Gillespie, Blair F. Johnston, Simon P. Mackay, Geoffrey D. Coxon |
| Abstract |
Tuberculosis (TB) is a disease which kills two million people every year and infects approximately over one-third of the world's population. The difficulty in managing tuberculosis is the prolonged treatment duration, the emergence of drug resistance and co-infection with HIV/AIDS. Tuberculosis control requires new drugs that act at novel drug targets to help combat resistant forms of Mycobacterium tuberculosis and reduce treatment duration. |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 3% |
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 60 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 22% |
| Student > Ph. D. Student | 13 | 20% |
| Student > Bachelor | 5 | 8% |
| Student > Postgraduate | 5 | 8% |
| Other | 4 | 6% |
| Other | 13 | 20% |
| Unknown | 10 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 18 | 28% |
| Agricultural and Biological Sciences | 12 | 19% |
| Medicine and Dentistry | 10 | 16% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Business, Management and Accounting | 1 | 2% |
| Other | 4 | 6% |
| Unknown | 17 | 27% |