| Title |
INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis
|
|---|---|
| Published in |
PLOS ONE, April 2009
|
| DOI | 10.1371/journal.pone.0005027 |
| Pubmed ID | |
| Authors |
Yan Liu, Hanna K. Sanoff, Hyunsoon Cho, Christin E. Burd, Chad Torrice, Karen L. Mohlke, Joseph G. Ibrahim, Nancy E. Thomas, Norman E. Sharpless |
| Abstract |
Genome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21 near the INK4/ARF (CDKN2A/B) tumor suppressor locus with risk of atherosclerotic diseases and type 2 diabetes mellitus. To explore the mechanism of this association, we investigated whether expression of proximate transcripts (p16(INK4a), p15(INK4b), ARF, ANRIL and MTAP) correlate with genotype of representative 9p21 SNPs. |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Hungary | 1 | <1% |
| Uruguay | 1 | <1% |
| Unknown | 131 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 31 | 23% |
| Student > Ph. D. Student | 26 | 19% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 11 | 8% |
| Student > Doctoral Student | 6 | 4% |
| Other | 25 | 19% |
| Unknown | 20 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 31% |
| Biochemistry, Genetics and Molecular Biology | 30 | 22% |
| Medicine and Dentistry | 24 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 1% |
| Immunology and Microbiology | 2 | 1% |
| Other | 7 | 5% |
| Unknown | 28 | 21% |