| Title |
Mitochondrial Variants in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
|
|---|---|
| Published in |
PLOS ONE, March 2009
|
| DOI | 10.1371/journal.pone.0004913 |
| Pubmed ID | |
| Authors |
Brandi Rollins, Maureen V. Martin, P. Adolfo Sequeira, Emily A. Moon, Ling Z. Morgan, Stanley J. Watson, Alan Schatzberg, Huda Akil, Richard M. Myers, Edward G. Jones, Douglas C. Wallace, William E. Bunney, Marquis P. Vawter |
| Abstract |
Mitochondria provide most of the energy for brain cells by the process of oxidative phosphorylation. Mitochondrial abnormalities and deficiencies in oxidative phosphorylation have been reported in individuals with schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD) in transcriptomic, proteomic, and metabolomic studies. Several mutations in mitochondrial DNA (mtDNA) sequence have been reported in SZ and BD patients. |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 3% |
| Brazil | 2 | 1% |
| United Kingdom | 2 | 1% |
| Canada | 2 | 1% |
| Chile | 1 | <1% |
| Germany | 1 | <1% |
| Mexico | 1 | <1% |
| New Zealand | 1 | <1% |
| Unknown | 174 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 35 | 18% |
| Student > Ph. D. Student | 32 | 17% |
| Student > Bachelor | 25 | 13% |
| Student > Master | 18 | 9% |
| Student > Doctoral Student | 16 | 8% |
| Other | 42 | 22% |
| Unknown | 22 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 58 | 31% |
| Medicine and Dentistry | 33 | 17% |
| Biochemistry, Genetics and Molecular Biology | 25 | 13% |
| Neuroscience | 21 | 11% |
| Psychology | 9 | 5% |
| Other | 17 | 9% |
| Unknown | 27 | 14% |