| Title |
C/EBPβ Promotes Transition from Proliferation to Hypertrophic Differentiation of Chondrocytes through Transactivation of p57Kip2
|
|---|---|
| Published in |
PLOS ONE, February 2009
|
| DOI | 10.1371/journal.pone.0004543 |
| Pubmed ID | |
| Authors |
Makoto Hirata, Fumitaka Kugimiya, Atsushi Fukai, Shinsuke Ohba, Naohiro Kawamura, Toru Ogasawara, Yosuke Kawasaki, Taku Saito, Fumiko Yano, Toshiyuki Ikeda, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguchi |
| Abstract |
Although transition from proliferation to hypertrophic differentiation of chondrocytes is a crucial step for endochondral ossification in physiological skeletal growth and pathological disorders like osteoarthritis, the underlying mechanism remains an enigma. This study investigated the role of the transcription factor CCAAT/enhancer-binding protein beta (C/EBPbeta) in chondrocytes during endochondral ossification. |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 22% |
| Student > Ph. D. Student | 8 | 22% |
| Student > Doctoral Student | 4 | 11% |
| Lecturer | 4 | 11% |
| Student > Bachelor | 2 | 6% |
| Other | 5 | 14% |
| Unknown | 5 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 15 | 42% |
| Biochemistry, Genetics and Molecular Biology | 7 | 19% |
| Medicine and Dentistry | 6 | 17% |
| Immunology and Microbiology | 2 | 6% |
| Nursing and Health Professions | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 5 | 14% |