Title |
LC/MS-Based Quantitative Proteomic Analysis of Paraffin-Embedded Archival Melanomas Reveals Potential Proteomic Biomarkers Associated with Metastasis
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Published in |
PLOS ONE, February 2009
|
DOI | 10.1371/journal.pone.0004430 |
Pubmed ID | |
Authors |
Sharon K. Huang, Marlene M. Darfler, Michael B. Nicholl, Jinsam You, Kerry G. Bemis, Tony J. Tegeler, Mu Wang, Jean-Pierre Wery, Kelly K. Chong, Linhda Nguyen, Richard A. Scolyer, Dave S. B. Hoon |
Abstract |
Melanoma metastasis status is highly associated with the overall survival of patients; yet, little is known about proteomic changes during melanoma tumor progression. To better understand the changes in protein expression involved in melanoma progression and metastasis, and to identify potential biomarkers, we conducted a global quantitative proteomic analysis on archival metastatic and primary melanomas. |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Spain | 1 | 1% |
United States | 1 | 1% |
Unknown | 79 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 24% |
Student > Ph. D. Student | 19 | 23% |
Professor > Associate Professor | 7 | 9% |
Student > Bachelor | 6 | 7% |
Student > Doctoral Student | 5 | 6% |
Other | 12 | 15% |
Unknown | 13 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 32% |
Medicine and Dentistry | 14 | 17% |
Biochemistry, Genetics and Molecular Biology | 6 | 7% |
Chemistry | 5 | 6% |
Neuroscience | 2 | 2% |
Other | 12 | 15% |
Unknown | 17 | 21% |