| Title |
Cytotoxicity Mechanism of Two Naphthoquinones (Menadione and Plumbagin) in Saccharomyces cerevisiae
|
|---|---|
| Published in |
PLOS ONE, December 2008
|
| DOI | 10.1371/journal.pone.0003999 |
| Pubmed ID | |
| Authors |
Frederico Augusto Vieira Castro, Diana Mariani, Anita Dolly Panek, Elis Cristina Araújo Eleutherio, Marcos Dias Pereira |
| Abstract |
Quinones are compounds extensively used in studies of oxidative stress due to their role in plants as chemicals for defense. These compounds are of great interest for pharmacologists and scientists, in general, because several cancer chemotherapeutic agents contain the quinone nucleus. However, due to differences in structures and diverse pharmacological effects, the exact toxicity mechanisms exerted by quinones are far from elucidatation. |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 1% |
| India | 2 | 1% |
| United States | 2 | 1% |
| Canada | 1 | <1% |
| China | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 129 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 29 | 21% |
| Student > Ph. D. Student | 28 | 20% |
| Student > Master | 17 | 12% |
| Student > Bachelor | 14 | 10% |
| Student > Doctoral Student | 8 | 6% |
| Other | 21 | 15% |
| Unknown | 21 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 50 | 36% |
| Biochemistry, Genetics and Molecular Biology | 35 | 25% |
| Chemistry | 8 | 6% |
| Medicine and Dentistry | 6 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 10 | 7% |
| Unknown | 26 | 19% |