| Title |
Trans-Translation in Helicobacter pylori: Essentiality of Ribosome Rescue and Requirement of Protein Tagging for Stress Resistance and Competence
|
|---|---|
| Published in |
PLOS ONE, November 2008
|
| DOI | 10.1371/journal.pone.0003810 |
| Pubmed ID | |
| Authors |
Marie Thibonnier, Jean-Michel Thiberge, Hilde De Reuse |
| Abstract |
The ubiquitous bacterial trans-translation is one of the most studied quality control mechanisms. Trans-translation requires two specific factors, a small RNA SsrA (tmRNA) and a protein co-factor SmpB, to promote the release of ribosomes stalled on defective mRNAs and to add a specific tag sequence to aberrant polypeptides to direct them to degradation pathways. Helicobacter pylori is a pathogen persistently colonizing a hostile niche, the stomach of humans. |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| Switzerland | 2 | 3% |
| Unknown | 67 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 23% |
| Researcher | 12 | 17% |
| Student > Bachelor | 9 | 13% |
| Student > Doctoral Student | 5 | 7% |
| Other | 5 | 7% |
| Other | 15 | 21% |
| Unknown | 9 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 38% |
| Biochemistry, Genetics and Molecular Biology | 21 | 30% |
| Medicine and Dentistry | 4 | 6% |
| Linguistics | 2 | 3% |
| Arts and Humanities | 1 | 1% |
| Other | 5 | 7% |
| Unknown | 11 | 15% |