| Title |
Detection of microRNA Expression in Human Peripheral Blood Microvesicles
|
|---|---|
| Published in |
PLOS ONE, November 2008
|
| DOI | 10.1371/journal.pone.0003694 |
| Pubmed ID | |
| Authors |
Melissa Piper Hunter, Noura Ismail, Xiaoli Zhang, Baltazar D. Aguda, Eun Joo Lee, Lianbo Yu, Tao Xiao, Jeffrey Schafer, Mei-Ling Ting Lee, Thomas D. Schmittgen, S. Patrick Nana-Sinkam, David Jarjoura, Clay B. Marsh |
| Abstract |
MicroRNAs (miRNA) are small non-coding RNAs that regulate translation of mRNA and protein. Loss or enhanced expression of miRNAs is associated with several diseases, including cancer. However, the identification of circulating miRNA in healthy donors is not well characterized. Microvesicles, also known as exosomes or microparticles, circulate in the peripheral blood and can stimulate cellular signaling. In this study, we hypothesized that under normal healthy conditions, microvesicles contain miRNAs, contributing to biological homeostasis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,021 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 7 | <1% |
| United Kingdom | 7 | <1% |
| United States | 5 | <1% |
| Netherlands | 5 | <1% |
| India | 4 | <1% |
| Brazil | 4 | <1% |
| Italy | 3 | <1% |
| Denmark | 3 | <1% |
| France | 2 | <1% |
| Other | 22 | 2% |
| Unknown | 959 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 214 | 21% |
| Researcher | 208 | 20% |
| Student > Master | 125 | 12% |
| Student > Bachelor | 97 | 10% |
| Student > Doctoral Student | 95 | 9% |
| Other | 155 | 15% |
| Unknown | 127 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 340 | 33% |
| Medicine and Dentistry | 203 | 20% |
| Biochemistry, Genetics and Molecular Biology | 177 | 17% |
| Neuroscience | 20 | 2% |
| Immunology and Microbiology | 19 | 2% |
| Other | 98 | 10% |
| Unknown | 164 | 16% |