| Title |
In Vitro Identification and Characterization of CD133pos Cancer Stem-Like Cells in Anaplastic Thyroid Carcinoma Cell Lines
|
|---|---|
| Published in |
PLOS ONE, October 2008
|
| DOI | 10.1371/journal.pone.0003544 |
| Pubmed ID | |
| Authors |
Giovanni Zito, Pierina Richiusa, Alessandra Bommarito, Elvira Carissimi, Leonardo Russo, Antonina Coppola, Monica Zerilli, Vito Rodolico, Angela Criscimanna, Marco Amato, Giuseppe Pizzolanti, Aldo Galluzzo, Carla Giordano |
| Abstract |
Recent publications suggest that neoplastic initiation and growth are dependent on a small subset of cells, termed cancer stem cells (CSCs). Anaplastic Thyroid Carcinoma (ATC) is a very aggressive solid tumor with poor prognosis, characterized by high dedifferentiation. The existence of CSCs might account for the heterogeneity of ATC lesions. CD133 has been identified as a stem cell marker for normal and cancerous tissues, although its biological function remains unknown. |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 2% |
| Italy | 1 | 2% |
| Romania | 1 | 2% |
| Taiwan | 1 | 2% |
| Unknown | 46 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 22% |
| Student > Ph. D. Student | 10 | 20% |
| Student > Bachelor | 4 | 8% |
| Professor | 4 | 8% |
| Professor > Associate Professor | 4 | 8% |
| Other | 8 | 16% |
| Unknown | 9 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 42% |
| Agricultural and Biological Sciences | 9 | 18% |
| Biochemistry, Genetics and Molecular Biology | 7 | 14% |
| Chemistry | 2 | 4% |
| Immunology and Microbiology | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 9 | 18% |