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Rapid Molecular Detection of Rifampicin Resistance Facilitates Early Diagnosis and Treatment of Multi-Drug Resistant Tuberculosis: Case Control Study

Overview of attention for article published in PLOS ONE, September 2008
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Title
Rapid Molecular Detection of Rifampicin Resistance Facilitates Early Diagnosis and Treatment of Multi-Drug Resistant Tuberculosis: Case Control Study
Published in
PLOS ONE, September 2008
DOI 10.1371/journal.pone.0003173
Pubmed ID
Authors

Philly O'Riordan, Uli Schwab, Sarah Logan, Graham Cooke, Robert J. Wilkinson, Robert N. Davidson, Paul Bassett, Robert Wall, Geoffrey Pasvol, Katie L. Flanagan

Abstract

Multi-drug resistant tuberculosis (MDR-TB) is a major public health concern since diagnosis is often delayed, increasing the risk of spread to the community and health care workers. Treatment is prolonged, and the total cost of treating a single case is high. Diagnosis has traditionally relied upon clinical suspicion, based on risk factors and culture with sensitivity testing, a process that can take weeks or months. Rapid diagnostic molecular techniques have the potential to shorten the time to commencing appropriate therapy, but have not been put to the test under field conditions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nepal 1 1%
Kenya 1 1%
South Africa 1 1%
United Kingdom 1 1%
Canada 1 1%
Japan 1 1%
Unknown 94 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 20%
Student > Master 20 20%
Student > Ph. D. Student 16 16%
Professor > Associate Professor 6 6%
Student > Postgraduate 5 5%
Other 20 20%
Unknown 13 13%
Readers by discipline Count As %
Medicine and Dentistry 39 39%
Agricultural and Biological Sciences 14 14%
Immunology and Microbiology 10 10%
Biochemistry, Genetics and Molecular Biology 7 7%
Nursing and Health Professions 2 2%
Other 9 9%
Unknown 19 19%