Title |
Rapid Molecular Detection of Rifampicin Resistance Facilitates Early Diagnosis and Treatment of Multi-Drug Resistant Tuberculosis: Case Control Study
|
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Published in |
PLOS ONE, September 2008
|
DOI | 10.1371/journal.pone.0003173 |
Pubmed ID | |
Authors |
Philly O'Riordan, Uli Schwab, Sarah Logan, Graham Cooke, Robert J. Wilkinson, Robert N. Davidson, Paul Bassett, Robert Wall, Geoffrey Pasvol, Katie L. Flanagan |
Abstract |
Multi-drug resistant tuberculosis (MDR-TB) is a major public health concern since diagnosis is often delayed, increasing the risk of spread to the community and health care workers. Treatment is prolonged, and the total cost of treating a single case is high. Diagnosis has traditionally relied upon clinical suspicion, based on risk factors and culture with sensitivity testing, a process that can take weeks or months. Rapid diagnostic molecular techniques have the potential to shorten the time to commencing appropriate therapy, but have not been put to the test under field conditions. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Nepal | 1 | 1% |
Kenya | 1 | 1% |
South Africa | 1 | 1% |
United Kingdom | 1 | 1% |
Canada | 1 | 1% |
Japan | 1 | 1% |
Unknown | 94 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 20% |
Student > Master | 20 | 20% |
Student > Ph. D. Student | 16 | 16% |
Professor > Associate Professor | 6 | 6% |
Student > Postgraduate | 5 | 5% |
Other | 20 | 20% |
Unknown | 13 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 39 | 39% |
Agricultural and Biological Sciences | 14 | 14% |
Immunology and Microbiology | 10 | 10% |
Biochemistry, Genetics and Molecular Biology | 7 | 7% |
Nursing and Health Professions | 2 | 2% |
Other | 9 | 9% |
Unknown | 19 | 19% |