Title |
High-Resolution, In Vivo Magnetic Resonance Imaging of Drosophila at 18.8 Tesla
|
---|---|
Published in |
PLOS ONE, July 2008
|
DOI | 10.1371/journal.pone.0002817 |
Pubmed ID | |
Authors |
Brian Null, Corey W. Liu, Maj Hedehus, Steven Conolly, Ronald W. Davis |
Abstract |
High resolution MRI of live Drosophila was performed at 18.8 Tesla, with a field of view less than 5 mm, and administration of manganese or gadolinium-based contrast agents. This study demonstrates the feasibility of MR methods for imaging the fruit fly Drosophila with an NMR spectrometer, at a resolution relevant for undertaking future studies of the Drosophila brain and other organs. The fruit fly has long been a principal model organism for elucidating biology and disease, but without capabilities like those of MRI. This feasibility marks progress toward the development of new in vivo research approaches in Drosophila without the requirement for light transparency or destructive assays. |
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Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 5% |
United Kingdom | 1 | 2% |
France | 1 | 2% |
Italy | 1 | 2% |
Unknown | 50 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 17 | 30% |
Student > Ph. D. Student | 14 | 25% |
Professor | 6 | 11% |
Professor > Associate Professor | 5 | 9% |
Student > Master | 4 | 7% |
Other | 9 | 16% |
Unknown | 1 | 2% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 13% |
Biochemistry, Genetics and Molecular Biology | 5 | 9% |
Engineering | 5 | 9% |
Chemistry | 4 | 7% |
Other | 10 | 18% |
Unknown | 1 | 2% |