| Title |
Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51
|
|---|---|
| Published in |
PLOS ONE, July 2008
|
| DOI | 10.1371/journal.pone.0002636 |
| Pubmed ID | |
| Authors |
Yimin Wu, Ruth D. Ellis, Donna Shaffer, Erica Fontes, Elissa M. Malkin, Siddhartha Mahanty, Michael P. Fay, David Narum, Kelly Rausch, Aaron P. Miles, Joan Aebig, Andrew Orcutt, Olga Muratova, Guanhong Song, Lynn Lambert, Daming Zhu, Kazutoyo Miura, Carole Long, Allan Saul, Louis H. Miller, Anna P. Durbin |
| Abstract |
Pfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites P. falciparum and P. vivax, respectively, are leading candidates for vaccines preventing malaria transmission by mosquitoes. This single blinded, dose escalating, controlled Phase 1 study assessed the safety and immunogenicity of recombinant Pfs25 and Pvs25 formulated with Montanide ISA 51, a water-in-oil emulsion. |
Mendeley readers
The data shown below were compiled from readership statistics for 274 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| Senegal | 1 | <1% |
| France | 1 | <1% |
| India | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 268 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 20% |
| Student > Master | 47 | 17% |
| Researcher | 39 | 14% |
| Student > Bachelor | 30 | 11% |
| Other | 20 | 7% |
| Other | 31 | 11% |
| Unknown | 52 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 69 | 25% |
| Biochemistry, Genetics and Molecular Biology | 40 | 15% |
| Medicine and Dentistry | 37 | 14% |
| Immunology and Microbiology | 24 | 9% |
| Engineering | 10 | 4% |
| Other | 32 | 12% |
| Unknown | 62 | 23% |