| Title |
On the Prevalence of M. avium Subspecies paratuberculosis DNA in the Blood of Healthy Individuals and Patients with Inflammatory Bowel Disease
|
|---|---|
| Published in |
PLOS ONE, July 2008
|
| DOI | 10.1371/journal.pone.0002537 |
| Pubmed ID | |
| Authors |
Ramon A. Juste, Natalia Elguezabal, Joseba M. Garrido, Andres Pavon, Maria V. Geijo, Iker Sevilla, Jose-Luis Cabriada, Angel Tejada, Francisco García-Campos, Roberto Casado, Itziar Ochotorena, Ander Izeta, Robert J. Greenstein |
| Abstract |
Mycobacteria, such as M. leprae and M. tuberculosis infect billions of humans. However, because of appropriate immune responses and antibiotic therapy, overt mycobacterial diseases occur far less frequently. M. avium subspecies paratuberculosis (MAP) causes Johne's disease in ruminants, an affliction evocative of inflammatory bowel disease (IBD). Several agents used to treat IBD (5-ASA, methotrexate, azathioprine and its metabolite 6-MP) have recently been shown to be antiMAP antibiotics. We herein evaluate the prevalence of MAP DNA in healthy individuals and compare them with IBD patients on antiMAP antibiotics. |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| Colombia | 1 | 2% |
| Australia | 1 | 2% |
| Qatar | 1 | 2% |
| Unknown | 54 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 20% |
| Researcher | 11 | 19% |
| Student > Master | 8 | 14% |
| Student > Postgraduate | 4 | 7% |
| Student > Bachelor | 3 | 5% |
| Other | 12 | 20% |
| Unknown | 9 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 36% |
| Medicine and Dentistry | 9 | 15% |
| Immunology and Microbiology | 6 | 10% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Nursing and Health Professions | 3 | 5% |
| Other | 8 | 14% |
| Unknown | 7 | 12% |