| Title |
Novel Peptide Marker Corresponding to Salivary Protein gSG6 Potentially Identifies Exposure to Anopheles Bites
|
|---|---|
| Published in |
PLOS ONE, June 2008
|
| DOI | 10.1371/journal.pone.0002472 |
| Pubmed ID | |
| Authors |
Anne Poinsignon, Sylvie Cornelie, Montserrat Mestres-Simon, Alessandra Lanfrancotti, Marie Rossignol, Denis Boulanger, Badara Cisse, Cheikh Sokhna, Bruno Arcà, François Simondon, Franck Remoue |
| Abstract |
In order to improve malaria control, and under the aegis of WHO recommendations, many efforts are being devoted to developing new tools for identifying geographic areas with high risk of parasite transmission. Evaluation of the human antibody response to arthropod salivary proteins could be an epidemiological indicator of exposure to vector bites, and therefore to risk of pathogen transmission. In the case of malaria, which is transmitted only by anopheline mosquitoes, maximal specificity could be achieved through identification of immunogenic proteins specific to the Anopheles genus. The objective of the present study was to determine whether the IgG response to the Anopheles gambiae gSG6 protein, from its recombinant form to derived synthetic peptides, could be an immunological marker of exposure specific to Anopheles gambiae bites. |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| United States | 1 | 1% |
| France | 1 | 1% |
| Unknown | 81 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 21 | 25% |
| Researcher | 16 | 19% |
| Student > Ph. D. Student | 12 | 14% |
| Student > Bachelor | 7 | 8% |
| Other | 5 | 6% |
| Other | 10 | 12% |
| Unknown | 13 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 29% |
| Biochemistry, Genetics and Molecular Biology | 17 | 20% |
| Immunology and Microbiology | 9 | 11% |
| Medicine and Dentistry | 6 | 7% |
| Environmental Science | 5 | 6% |
| Other | 9 | 11% |
| Unknown | 14 | 17% |