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Why Are Clinicians Not Embracing the Results from Pivotal Clinical Trials in Severe Sepsis? A Bayesian Analysis

Overview of attention for article published in PLOS ONE, May 2008
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Title
Why Are Clinicians Not Embracing the Results from Pivotal Clinical Trials in Severe Sepsis? A Bayesian Analysis
Published in
PLOS ONE, May 2008
DOI 10.1371/journal.pone.0002291
Pubmed ID
Authors

Andre C. Kalil, Junfeng Sun

Abstract

Five pivotal clinical trials (Intensive Insulin Therapy; Recombinant Human Activated Protein C [rhAPC]; Low-Tidal Volume; Low-Dose Steroid; Early Goal-Directed Therapy [EGDT]) demonstrated mortality reduction in patients with severe sepsis and expert guidelines have recommended them to clinical practice. Yet, the adoption of these therapies remains low among clinicians.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 4%
Brazil 2 4%
United States 1 2%
Unknown 44 90%

Demographic breakdown

Readers by professional status Count As %
Other 9 18%
Student > Ph. D. Student 7 14%
Student > Postgraduate 5 10%
Student > Master 5 10%
Researcher 4 8%
Other 13 27%
Unknown 6 12%
Readers by discipline Count As %
Medicine and Dentistry 33 67%
Nursing and Health Professions 2 4%
Engineering 2 4%
Social Sciences 2 4%
Philosophy 1 2%
Other 0 0%
Unknown 9 18%