| Title |
Anti-Inflammatory Preconditioning by Agonists of Adenosine A1 Receptor
|
|---|---|
| Published in |
PLOS ONE, May 2008
|
| DOI | 10.1371/journal.pone.0002107 |
| Pubmed ID | |
| Authors |
Sigal Nakav, Cidio Chaimovitz, Yuval Sufaro, Eli C. Lewis, Gad Shaked, David Czeiger, Moshe Zlotnik, Amos Douvdevani |
| Abstract |
Adenosine levels rise during inflammation and modulate inflammatory responses by engaging with four different G protein-coupled receptors. It is suggested that adenosine exhibits pro-inflammatory effects through its A(1) receptor (A(1)R), and anti-inflammatory effects through A(2A) receptor (A(2A)R). Therefore, understanding of the mechanisms that govern adenosine receptor regulation may advance treatment of various inflammatory disorders. We previously reported that peak A(1)R expression during leukocyte recruitment, is followed by a peak in A(2A)R during inflammation resolution. |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 54 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 22% |
| Student > Bachelor | 9 | 16% |
| Professor | 6 | 11% |
| Student > Master | 5 | 9% |
| Researcher | 4 | 7% |
| Other | 5 | 9% |
| Unknown | 14 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 25% |
| Biochemistry, Genetics and Molecular Biology | 6 | 11% |
| Neuroscience | 6 | 11% |
| Medicine and Dentistry | 5 | 9% |
| Chemistry | 4 | 7% |
| Other | 6 | 11% |
| Unknown | 14 | 25% |