| Title |
Ethnic Related Selection for an ADH Class I Variant within East Asia
|
|---|---|
| Published in |
PLOS ONE, April 2008
|
| DOI | 10.1371/journal.pone.0001881 |
| Pubmed ID | |
| Authors |
Hui Li, Sheng Gu, Xiaoyun Cai, William C. Speed, Andrew J. Pakstis, Efim I. Golub, Judith R. Kidd, Kenneth K. Kidd |
| Abstract |
The alcohol dehydrogenases (ADH) are widely studied enzymes and the evolution of the mammalian gene cluster encoding these enzymes is also well studied. Previous studies have shown that the ADH1B*47His allele at one of the seven genes in humans is associated with a decrease in the risk of alcoholism and the core molecular region with this allele has been selected for in some East Asian populations. As the frequency of ADH1B*47His is highest in East Asia, and very low in most of the rest of the world, we have undertaken more detailed investigation in this geographic region. |
X Demographics
The data shown below were collected from the profiles of 127 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 39 | 31% |
| China | 2 | 2% |
| North Macedonia | 1 | <1% |
| Sweden | 1 | <1% |
| Unknown | 84 | 66% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 121 | 95% |
| Scientists | 5 | 4% |
| Practitioners (doctors, other healthcare professionals) | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 7% |
| France | 1 | 1% |
| Unknown | 67 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 21% |
| Researcher | 14 | 19% |
| Student > Bachelor | 12 | 16% |
| Student > Master | 6 | 8% |
| Other | 4 | 5% |
| Other | 9 | 12% |
| Unknown | 13 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 36% |
| Biochemistry, Genetics and Molecular Biology | 14 | 19% |
| Medicine and Dentistry | 6 | 8% |
| Social Sciences | 4 | 5% |
| Mathematics | 2 | 3% |
| Other | 7 | 10% |
| Unknown | 14 | 19% |