| Title |
Vaccination Targeting a Surface Sialidase of P. acnes: Implication for New Treatment of Acne Vulgaris
|
|---|---|
| Published in |
PLOS ONE, February 2008
|
| DOI | 10.1371/journal.pone.0001551 |
| Pubmed ID | |
| Authors |
Teruaki Nakatsuji, Yu-Tsueng Liu, Cheng-Po Huang, Christos C Zouboulis, Richard L Gallo, Chun-Ming Huang |
| Abstract |
Acne vulgaris afflicts more than fifty million people in the United State and the severity of this disorder is associated with the immune response to Propionibacterium acnes (P. acnes). Systemic therapies for acne target P. acnes using antibiotics, or target the follicle with retinoids such as isotretinoin. The latter systemic treatment is highly effective but also carries a risk of side effects including immune imbalance, hyperlipidemia, and teratogenicity. Despite substantial research into potential new therapies for this common disease, vaccines against acne vulgaris are not yet available. |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 2 | 3% |
| United Kingdom | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 76 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 24% |
| Student > Master | 9 | 11% |
| Other | 6 | 8% |
| Student > Bachelor | 6 | 8% |
| Student > Ph. D. Student | 5 | 6% |
| Other | 16 | 20% |
| Unknown | 19 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 28% |
| Medicine and Dentistry | 13 | 16% |
| Immunology and Microbiology | 9 | 11% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Other | 8 | 10% |
| Unknown | 20 | 25% |