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A Ribosomal S-6 Kinase–Mediated Signal to C/EBP-β Is Critical for the Development of Liver Fibrosis

Overview of attention for article published in PLOS ONE, December 2007
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Title
A Ribosomal S-6 Kinase–Mediated Signal to C/EBP-β Is Critical for the Development of Liver Fibrosis
Published in
PLOS ONE, December 2007
DOI 10.1371/journal.pone.0001372
Pubmed ID
Authors

Martina Buck, Mario Chojkier

Abstract

In response to liver injury, hepatic stellate cell (HSC) activation causes excessive liver fibrosis. Here we show that activation of RSK and phosphorylation of C/EBPbeta on Thr217 in activated HSC is critical for the progression of liver fibrosis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 31%
Student > Master 4 13%
Student > Ph. D. Student 3 9%
Professor > Associate Professor 3 9%
Professor 2 6%
Other 4 13%
Unknown 6 19%
Readers by discipline Count As %
Medicine and Dentistry 11 34%
Agricultural and Biological Sciences 9 28%
Biochemistry, Genetics and Molecular Biology 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Chemistry 1 3%
Other 1 3%
Unknown 6 19%